Formulation and Pharmacological Evaluation of a Herbal Ointment Containing Blepharis repens for Topical Therapeutic Applications

Herbal Ointment of Blepharis repens: Formulation and Pharmacological Evaluation

Abstract

Blepharis repens, commonly known as Hadsan in Marathi, is a medicinal herb from the Acanthaceae family, predominantly found in arid and rocky regions of India. Traditionally, it is utilized in managing bone fractures, dermatological conditions, urinary disorders, and allergic reactions. In the present study, an herbal ointment was formulated using the fusion method from various parts of Blepharis repens, focusing on its wound-healing potential. The formulation was systematically evaluated for its physicochemical properties, stability, and therapeutic relevance. Phytochemical screening revealed the presence of bioactive compounds including flavonoids, tannins, and saponins, known for their anti-inflammatory, antioxidant, and regenerative activities. Notably, the leaves exhibited significant wound-healing and anti-inflammatory effects, while the roots demonstrated bone-regenerative properties. These findings provide preliminary scientific support for the traditional topical use of Blepharis repens and underscore its potential in herbal dermatological formulations.