Synthesis, Characterization, and Therapeutic Potential of Biogenic Silver Nanoparticles Using Ashwagandha Extract

Abstract

This review provides a thorough examination of the synthesis, characterization, and therapeutic applications of biogenic silver nanoparticles derived from Ashwagandha (Withania somnifera). Ashwagandha, a renowned medicinal herb, holds immense potential in nanotechnology, offering a sustainable and eco-friendly route for synthesizing silver nanoparticles. The synthesis methods are scrutinized in detail, encompassing biological approaches that exploit the plant's inherent bioactive compounds. Characterization techniques, crucial for understanding the physicochemical properties of these nanoparticles, are meticulously analyzed. From spectroscopic methods to microscopy and size distribution analyses, the comprehensive evaluation ensures a nuanced understanding of the structural attributes of Ashwagandha-induced silver nanoparticles. The therapeutic applications constitute a focal point, exploring the diverse biomedical and pharmaceutical arenas where these nanoparticles exhibit promising potential. Their antimicrobial, anti-inflammatory, and antioxidant properties are highlighted, offering insights into their role in combating various diseases. Moreover, their biocompatibility and low toxicity make them attractive candidates for drug delivery systems. This in-depth analysis synthesizes current research, addressing challenges and proposing future directions. By bridging the realms of traditional medicine and modern nanotechnology, the review underscores the significance of Ashwagandha-derived silver nanoparticles, paving the way for innovative and sustainable therapeutic strategies.